By: Mejia Yahaira
This summer, I had the privilege of being mentored by Bryan Kaplan, a Johns Hopkins University alumnus and the lab program manager at a Harvard-affiliated lab within Mass General Brigham. Our primary focus was on conducting histopathological experiments related to Adenoid Cystic Carcinoma (ACC). ACC is the most common tumor found in the minor salivary glands and the second most common in the major salivary glands. ACC also manifests in the lacrimal gland of the eye, which is the specific area our lab is investigating. Given the limited data on the predisposing risk factors and the management of advanced ACC cases, our research aims to fill this gap. Notably, ACC cells stain positive for markers such as SMA, S100, vimentin, MYB, and CD117, suggesting a possible involvement of the RUNX1 protein, which is a central focus of our lab’s studies.
A New World
Entering my summer internship in a medical-based wet lab, I faced the dual challenge of mastering complex scientific techniques while also trying to connect with colleagues in a new and unfamiliar environment. As the youngest and least experienced member of the team, I initially felt overwhelmed and unsure of how to navigate both the technical demands and the social dynamics of the lab. However, I set clear goals for myself: to develop meaningful relationships with my colleagues and to gain proficiency in the lab’s technical processes. By the end of the summer, I had not only achieved these goals but also experienced significant personal and professional growth.
My primary project involved studying tissue micro-environments through various staining techniques, such as H&E and Masson’s Trichrome Staining, and performing Immunofluorescent staining to analyze mesenchymal markers. As I worked on these complex tasks, I made it a point to engage with my colleagues, learning from their expertise while also sharing my progress. This dual focus on technical work and relationship-building was initially challenging, but it ultimately led to a richer, more collaborative experience.
I found that as I became more comfortable with the technical aspects of my work, I also grew more confident in interacting with my colleagues. Small talk during lunch and after hours provided opportunities to learn about their personal lives, hobbies, and career aspirations. These conversations not only helped me build friendships but also enhanced our collaboration in the lab. For example, discussing project details over informal gatherings allowed me to gain new insights and ideas that I could apply to my work.
Beyond the lab, I participated in social activities, such as birthday celebrations and weekly basketball games, which further strengthened my connections with colleagues. These experiences taught me that building strong professional relationships can significantly enhance the work environment, making it more enjoyable and supportive. It also provided a break from the technical demands of the lab, allowing me to recharge and return to my work with renewed energy.
Skills and Knowledge
Throughout the internship, I honed my skills in various staining protocols, such as H&E, Masson’s Trichrome, and Immunofluorescent Staining, and applied them to both my primary project and other lab initiatives. I also learned cell culturing techniques, which enabled the lab to conduct important assays. These technical skills were crucial in contributing to the lab’s research and in helping me grow as a young scientist.
Equally important were the soft skills I developed, particularly in communication and networking. By actively engaging with my colleagues, I learned how to effectively share my findings, seek feedback, and collaborate on complex problems. These skills are not only applicable in a lab setting but will also be valuable in any future professional environment.
Impact of Objectives and Key Results
At the start of my internship, I set two main OKRs: to master key lab techniques and to build strong relationships with my colleagues. Tracking my progress towards these objectives kept me focused and motivated. I found that these goals were interrelated—improving my technical skills made me more confident in discussing my work with others, while building relationships provided a support network that enhanced my learning. Achieving these goals had a profound impact on my internship experience. On the technical side, I successfully performed staining protocols and contributed to significant lab projects, such as investigating RUNX1 in tissue samples. On the interpersonal side, I established genuine friendships with my colleagues, which made the lab feel like a community rather than just a workplace.
Lessons Learned
One of the key lessons I learned was the importance of balancing professional and personal development. While mastering technical skills was crucial, building relationships added depth and meaning to my experience. I realized that these two aspects are not mutually exclusive but rather complementary. By engaging with my colleagues, I gained not only technical knowledge but also a sense of belonging and support within the lab. Overcoming the initial challenges of shyness and inexperience taught me the value of perseverance and open communication. By pushing myself to engage both technically and socially, I was able to transform what initially felt like a daunting experience into one of significant personal and professional growth.
Into the Future
Moving forward, I plan to apply both the technical skills and the interpersonal lessons I’ve learned in my future academic and career pursuits. I now understand the importance of integrating technical proficiency with strong professional relationships, and I will continue to seek out environments that foster both. This experience has also influenced my career aspirations. I am now more interested in work environments that value collaboration and continuous learning. Whether in research or another field, I plan to build on the foundation I’ve established during this internship, focusing on both skill development and relationship-building.
Summer Ending
Reflecting on my summer internship, I am grateful for the dual growth I experienced—both in mastering technical skills and in building meaningful relationships with my colleagues. What started as a challenging and somewhat intimidating experience turned into a period of profound personal and professional development. For anyone considering a similar internship, I encourage you to set goals that encompass both technical mastery and interpersonal growth. This balanced approach can lead to a more fulfilling and successful experience. In all, I would like to thank my mentor, Bryan Kaplan, for the success I found in the lab and the lovely people in the life Design Lab who helped me “design” my summer experience.
